This session will discuss IT and OT threats to Connected Factories that happen through autonomous cars, intelligent transportation systems, smart buildings, port and maritime security vulnerabilities, as well as traditional malware and IoT attack vector. Offering both technological and policy-oriented recommendations to confronting vulnerabilities that smart manufacturing will face over the next five to ten years. With this analysis, we assess the countermeasures that individuals, businesses, and regional and national governments must consider to sustain and improve the quality of life for a connected world.